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Evaluation of the Differences of Myocardial Fibers between Acute and Chronic Myocardial Application of Diffusion Tensor Magnetic Resonance Imaging in a Rhesus Monkey Model.


Objective: To understand microstructural changes after myocardial infarction (MI), we evaluated myocardial fibers of rhesus monkeys during acute or chronic MI, and identified the differences of myocardial fibers between acute and chronic MI.

Conclusion: Diffusion tensor MRI method helps to quantify differences of mechanical microstructure and water diffusion of myocardial fibers between acute and chronic MI monkey’s models.

Keywords: Rhesus monkey; Myocardial fiber; Myocardial infarction; Helix angle; Diffusion tensor MR imaging; DTI


Fig. 2  Diffusion maps of myocardial fibers. Regions pointed by red arrows are MI regions. ADC = apparent diffusion coefficients, FA =fractional anisotropy, MI = myocardial infarction

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