Nonhuman primates are phylogenetically similar to humans including in lipid metabolism and lipid profiles. All humans and NHPs are susceptible to the development of diabetes and dyslipidemia from middle age.
Primed Spontaneous Dyslipidemia NHP Capability
Breeding center: n=~3000 rhesus macaques (macaca mulatta).
Colony of n=~700 dysmetabolic rhesus macaques.
Historical clinical /metabolic data (8yrs.)
Semiannual metabolic screenings.
Plasma and tissue biobank.
PCSK9 inhibitor, Ezetimibe and statins have been validated with our dyslipidemia NHP model.
Metabolic biomarker assay development and validation (HMG-COA reductase inhibitors, PCSK9 inhibitors, NPC1L1).
More than 40 compounds have been performed for a dozen international and domestic clients.
Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Nonhuman Primates (NHP’s) is Comparable to Humans for Metabolic Features, Histology and Imaging
Tel : +86-28-85921823
Fax : +86-28-62491302
Zip code : 610041