Sichuan PriMed Shines Bio-tech Co., Ltd., headquartered in Chengdu, China, is a Non-human Primate CRO with extensive research experiences of 12 years (2005-2017). PriMed Shines provides highest service to our clients in our 400,000 ft2 fully AAALAC accredited facilities.
Primed is a Cutting Edge Translational Research Company devoted to understanding and overcoming human diseases.
Primed has extensive expertise and significant experience in non-human primate research, as well as identifying and developing specialized animal models of human disease, helping global biomedical research community solve challenges in Metabolic disease, Eye disease, Cardiovascular diseases, NAFLD/NASH, Autoimmune diseases and Kidney disease.
Primed's research facilities are AAALAC accredited and GLP compliant, providing expertise from disease model validation to IND-enabling study design and execution for over 100 global partners.
Primed has well-established multi-modality imaging capabilities and extensive expertise in developing and applying imaging biomarkers for drug discovery and development with 11 different imaging modalities available for studies.
Primed's research center has (about n=~3000) NHPs with clearly pedigree and has set up a unique sizable (middle age/aged., equivalent to 40~70 years in human) rhesus macaques population (n= ~1500) with spontaneous metabolic, cardiovascular and ophthalmic disease phenotypes that translate well into clinical observations. More than 7 years' database of historical clinical data for all monkeys, including semiannual metabolic examination and plasma, tissue biobank.
Primed always invites collaborators to improve health of humans and NHPs. Our research brings hope to millions of patients.
PriMed Shines has built a fully-integrated monkey imaging center and translational research platforms for novel drug discovery. In total, 11 different imaging modalities are available for monkey studies.
PriMed Shines has access to 3.0T MRIs for cardiac and fibrosis imaging, dual-energy CT and Doppler ultrasound for cardiac and liver imaging studies. Other platforms available include dual-energy X-ray absorptiometry and eye imaging platform includes fundus camera, OCT and ERG. PriMed Shines has built an imaging database for over 400 dysmetabolic monkeys.
Key focused disease areas/ diabetic complications:
Cardiovascular diseases / Diabetic cardiomyopathy/ Diastolic dysfunction
Kidney diseases / Diabetic nephropathy
Liver diseases / NASH
Chronic pain / Diabetic neuropathy
Eyes diseases / Diabetic retinopathy / AMD
PriMed Shines Bio-tech has built a good relationship with more than 100 global partners including academic institutions, biotech companies, medium-sized pharmaceutical companies and Big Pharmas.
Over 200 compounds have been tested across our NHP models.
All procedures and practices following GLP general guidelines.
We invite collaborators all times. We are always interested in clinical questions as well as pharmaceutical questions. PriMed Shines will help you to make A Go or No-Go Decision and derisk the clinical development.